Re: Anyway to disable "e" button?
 

Yes there's an easy way to fix this for Dominions_3. Download Microsofts tool called Remapkey.exe. This tool is very easy to use and when you're finished playing Dominions_3 it's very easy to return the settings to normal.

Ideally Shift and e should end the turn instead of only e , perhaps a future patch.

Re: Anyway to disable "e" button?
 

A keyboard only costs like $12. Why don't you buy a spare keyboard, remove the "E" key, and just plug it in when playing Dominions? I don't get what all the fuss is about, that's simple.

Re: Anyway to disable "e" button?
 

On the other hand a program like AutoHotKey is free to download. And it can be setup to make the change automatically whenever you start Dom3, and turn it back when you quit. Still not the best answer but its an answer.