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Dolly the Cloned Sheep Dies
By Drog, Section News
Posted on Fri Feb 14th, 2003 at 12:50:40 PM EST

The world's most famous sheep has died. Dolly, who was the first animal to be cloned from an adult cell, was euthanized today. "She had a lung infection and it was quite serious. It is something that happens in sheep," Professor Ian Wilmut, of the Roslin Institute, told Reuters. "She had a detailed veterinary examination and they decided that because she wasn't going to recover. It was kinder to euthanize her. Sheep that are housed are at risk of infection. We housed her because of security and so we could observe her. Unfortunately other sheep who had been in the barn had also had this infection," Wilmut explained, adding that the infection most likely was transmitted from another animal in the barn. "We have to await the results of the post mortem."
Although Dolly's death may not have had anything to do with the fact that she was a clone, she had developed arthritis at an unusually young age, which raised concerns that it was due to a genetic defect caused by the cloning process. Some researchers suspect cloned animals may suffer from premature aging because cloning involves putting genes from a mature animal into an egg. Dolly was created by taking the nucleus out of a cell from the mammary gland of a six-year old ewe and fusing it, using an electrical current, into another sheep egg cell from which the nucleus had been transferred. Dr. Paul Shields and Dr. Ian Wilmut, in a letter to Nature, reported that Dolly's telomeres were 20 percent shorter than those of non-cloned sheep of a similar age. Telomeres are DNA strands at each end of a cell's DNA that become shorter with each cell division. Some scientists have speculated that telomeres are a biological clock that tell cells when it's time to stop dividing and die, but the process has been shown to be more complex in reality. A University of Hawaii experiment, which cloned successive generations of mice partially to test the premature aging theory, encountered no signs of premature aging until the fifth generation of clones. Dolly became a mother in April 1998 when she gave birth to her first lamb, a female called Bonnie, who has normal telomeres.

Yah, I read that.... How Ironic...

[ February 18, 2003, 06:22: Message edited by: ZeroAdunn ]

So cloning doesn't work. Good to know.

Not exactly, Aloofi.

Lung infections have nothing to do with cloning, its just a hazard of life in general.

Some of the other things like arthritis are probably related to her being cloned, but not the infection.

Cloning does work, just not anything like pop sci-fi would lead you to believe.
Its pretty much the same as if you had an identical twin brother or sister, and put them in cryo for a few years.

[ February 21, 2003, 18:48: Message edited by: Suicide Junkie ]

But lung infections are usually fatal only in old sheeps, more then 10y old. Dolly was 6. This plus unusally young arthritus makes it all worrisome.

So, you could still clone your best soldiers.
Just don't expect them to grow old and grey.

I'm being cynical (or realistic). http://forum.shrapnelgames.com/image...s/confused.gif

I just want to know if she tasted as good as non-cloned mutton.
Hahahaa!

Quote:

Originally posted by Tenryu:
I just want to know if she tasted as good as non-cloned mutton.
Hahahaa!

<font size="2" face="Verdana, Helvetica, sans-serif">Eewk!
I wouldn't taste that **** for a million bucks.....
Oh well, maybe for a million, after you taste it. http://forum.shrapnelgames.com/images/icons/icon10.gif

Quote:

So, you could still clone your best soldiers.
Just don't expect them to grow old and grey.

<font size="2" face="Verdana, Helvetica, sans-serif">Or to be trained from birth, or even to be useful for the first few decades.

Quote:

Originally posted by Suicide Junkie:
Or to be trained from birth, or even to be useful for the first few decades.

<font size="2" face="Verdana, Helvetica, sans-serif">They'd train a lot quicker if you moved them to Jupiter, since there are more moons there.

If dolly was full of crunchy-yummy goodness they would make more of her for us to eat.

> http://forum.shrapnelgames.com/images/icons/icon7.gif

Actually, I've devised this scheme, we clone the fastest strongest and brightest soldiers we can find, then when we put these helmets on them see, these helmets play back military doctorine, weapons technology, and various other things that would serve a soldier well. This whole time they are hooked up to machines like those ab tonners, only for the whole body, I figure, by age ten we have psychotics super warriors who know how to do nothing but conquer everything around them. We drop them on some poor unsuspecting country, they conquer it, then because they are clones of older people, they die by 20, and we come in and take control.....

My plan, is fool proof. http://forum.shrapnelgames.com/images/icons/tongue.gif

no its not, if you clone a fool the whole scheme would be screwed up http://forum.shrapnelgames.com/images/icons/tongue.gif

Pfft... foolishness is learned, not inherited... Oh, and all my soldiers will have six fingers on each hand, so we can have a base twelve number system in my military like our great alien ancestors.

How about eight fingers on each hand? Then they can count in hexadecimal; it would give them a huge advantage in learning computer science.

Naaah, us compsci majors can count in Hex with only 7 fingers... oh wait I mean 10
anyhow, the biggest reason clones die out fast is the telomere shortening... if you took young DNA, modified it, you could feasibly make a clone with good telomeres, or ever longer telomeres. Very Deus Ex like....