Units, units, units! Mines will do lots of damage without the formality of combat, and will still force her to use space in at least some of her ships for mine sweepers once she's got the first minefield reports. Satellites, drones, and fighters are all 'solid'. Individual components (armor or otherwise) are not counted in unit damage. The shard cannon is just a wimpier APB against units.
Other than leaning as heavily as possible on units, yes, seekers at max range are a good strategy. Especially in combination with fighters and drones. Over load those PDCs!
