To put it simple: If someone would tell me: "I have good and bad news. Good news is that you will live next 400 years. Bad news is that you can't have sex ever again.", I would propably kill myself.
Though, right now I might actually agree to that, because most propably cloning of body parts and alternate aging prevention systems are to be invented in near future, say during next 100 years. Then I would simply have new body(parts) I were missing and keep orgies never heard of
