Gods...
Since I have been avidly playing PC games since about 1987, I have more than I can begin recall.
So...
Ones I would be willing to play today:
Civilization
Colonization
MOO2 (well, not now

)
Red Baron (original)
Combat Mission: Beyond Overlord
Combat Mission: Beyond Barbarrosa
Great Naval Battles
Task Force 1942
Crusader 1 & 2
F15 SEII
F14
X-Com I (perhaps my all time favorite game)
Pacific Air War:1942
Tropico (still playing it)
Star Fleet Command 1 & 2
Neverwinter Nights
Darklands (loved enough to build a P&P RPG campaign with it)
Master of Magic (despite the cruddy AI)
Freedom Force
Machiavelli
Arcanum
Duke Nukem
Redneck Rampage (I live in the South, I know people like this)
Counter-Strike (oh so addicting)
Covert Action (I kid you not)
Hidden & Dangerous series
Half-Life
Pirates!
M.U.L.E
Interstate '76
Games I am looking forward to:
Combat Mission: Afrika Korps
Space Empires V
Silent Storm (very X-Com like, WWII flavor)
Hidden & Dangerous II
Half-Life 2
Pirates! II