I have a deep distrust in MSI mobos... As Ruatha has mentioned, no beeps at all is the bad sign hinting for a dead mobo.
First check: fans spinning? -> power supply ok, no shortcircuit on mobo (or stuck reset key, I had this one once too), fine.
Second: the mobo should do a number of beeps while checking the most basic things like cpu, memory, video card. In this case, number of beeps gives you the damaged part.
(Unless its an modern EPOX mainboard, which have a 2-digit display onboard displaying in hex the status while booting up, thus giving a hex code for the error at the point of failure. What luxury - I have come to hate counting numerous too-short beeps and probably even riddling about if it has been a long or short beep. Guess what Boards I currently prefer
)
If no beeps at all (speaker properly connected?) -> mobo does not even start properly with its BIOS. To make sure remove everything including RAM and CPU, try again. No beeps -> trash the mobo. You could try resuscitation, exert some moderate pressure on various parts of the mobo, especially on all socketed components, loosen the screws a bit - maybe its a hairline crack that fixes itself (hopefully for some time). But thats extreme luck if it should work.