Oh, I'm not trying to debate between a fated destiny and, say, a witch's curse. I'm just chattering about Celtic mythology. I'm alarmingly prone towards doing that.
(Although your comment about "the affairs of the gods" does make me want to comment on the fact the game is, indeed, about the affairs of the gods!
)
Still, that's not actually what I was trying to say. I, also, look on the Curse effect in Dominions as something a bit more . . . well, mortal, if that makes any sense at all. A
geis and the like are quite different from, say, having one's path crossed by a black cat.
That's another reason I think making Wish be able to remove Curses would be a good touch. It does seem like, unlike a true component of one's destiny, they should be removable by some kind of very powerful magic, and Wish couldn't be a better candidate.