[Daynarr]

Basically any flying commander (or pretender) or group of commanders can take out VQ if you equip them with cheap armor negating/piercing magical weapons. The whole idea is to strike at VQ on first turn before she buffs herself.

Another way is to use lots of lifeless summons (or units if you can buy them) that she can't drain. After VQ casts buffs, she will have pretty high fatigue - use that to swarm her with lifeless army. Of course, this is not doable at the very start.

Another good pretender to take out VQ is Virtue. She already comes with weapon for the job so you need only to equip her with couple of cheap items (like pendant of luck), have her attack fliers or cast mistform then to attack fliers.