[Arryn]

Another problem with using pixels rather than relative sizes is that it screws up the way the HTML font attributes (such as bold, etc.) are interpreted when small styles are selected.

And I understand what Esben is going through. I use a large monitor also and I had to switch from 1600x1200 down to 1280x1024, and select large/huge (not much difference between them) just to be able to read the forum without rather serious eyestrain.

Any study of CSS/HTML coding guides will tell you exactly what Esben has said: you don't use pixels unless there's a darn good reason to, *and* you're an expert web designer.