The technobable doesn't bother me at all. That's actually part of what I find appealing in Trek. And the idea of humans being a major player in the galaxy is just part of the overall story. I'm not complaining about a lack of realism, just a lack of consistancy within the franchise. We have an established history with the previous series. We know when certain things happened, and when certain races were first contacted. When Enterprise came out I was very excited about the prospect of filling in some of the blank spots and fleshing out the details of how the Federation came into being. The early episodes with the Andorians were excellent.
But then the crap with the temporal cold war, and the Ferengi, the Borg, the Organians, totally rewriting vulcan history.
Like many fans I like to view the star trek franchise as a continuum of stories set in a common universe. Like one big book with chapters written by different authors. But when stuff in one chapter totally contradicts stuff in another chapter, it just gets a little frustrating.