[Suicide Junkie]

TDM only works because it is not a mod, but rather a set of kickass AIs.

FQM could be spliced in I suppose, since P&N dosen't do much with the planets/systems/quadrants.

But nothing that changes components, facilities, shipsizes etc would be compatible. Not without making a whole new mod from scratch. And sometimes not even then; some feature sets are mutually exclusive.