[Frostmourne27]

Multiple attacks from one creature (in Dom2 at least) could be directed against any creature. However, you could never attack creatures in more than one square without an AOE or quickness. This was irrespective of whether the attacks came from multi-attack weapon or from multiple different weapons. I.E. A non-quickened no AOE attack commander could kill five hoburgs, or three men, or two cavalry, or one sphinx.