With SEIV I've created variants of the current systems.txt file (or whatever it's called), using planet names from Dune, planet names from the Foundation series (Asimov), planet names from the Star Trek universe and various RL "named stars" listings.
When I'm using planet names from my favorite Sct Fi novels as SEIV system names the systems then take on more importance in my eyes. It becomes "the battle for Horleggor," instead of the battle for some meaningless stock SEIV system name.
You can also use ancient city names, ancient diety names, etc etc.
Somebody suggested using small Russian cities. Heck, any country's cities will do. Turkish cities/towns, Central American/South American towns with Amerindian names, etc.
Creating new system name files is almost as much fun as creating new design.txt files.
