[Taqwus]

Hrm. One of the more sadistic weapon combinations I used combined an ionic disrupter (trashes engines (and only engines), but only medium range), null-space projectors (bypasses shields and armor, but short-medium range and takes significant time to reload) and a repulsor beam. It kills very slowly, but cripples quite readily. And crippled ships cost full maintenance...

(Incidentally, the same weapon mix would be pretty nasty for Deeply Religious starbases using the Talisman (100% hit) and heavy starbase mounts (extended range) -- they could immobilize attacking ships before the attackers get in range, and then fling 'em across the tactical map).