[Endoperez]

Many roguelikes, like Dungeon Crawl, use both unique, pre-defined artifacts (Ring of Shaolin, increases your defence +8) and randomly created items (from +2 spear, to +2 axe of chopping, to +4 axe of chopping 'Teuhha' which increases your eyesight, lets you go berserk and makes you vulnerable to cold). Something like that, but with generic items limited to trinket power, could work well.