Well, I did not have any problems to run the patch. At the time I applied it, I had four installations of SE4 on my computer (1.49, Gold Beta, and two 1.60 (one with mods included and one vanilla, which was about to be patched). Sure enough after a quick scan the patch.exe found exactly the one that I wanted

. Since the program asked for a verification, it would not have been a problem to select a different folder,either.
Rollo