Played quite a bit the other day with no problems (with 3.20).
Today I loaded up the game and the commander buttons on the left are not there, which makes it really hard to actually do anything
Restarting the game has them show up, but after a few minutes they disappear. I did change to windowed mode at one point, and that seemed to really screw up the short-cut keys, so I went back to full screen and thats when the weirdness began.
I'll probably do a fresh reinstall/patch, but just wondering if anyone else has had this happen to them.