Well "The Malediction" is obviously the rise of vampirism, which did lead to civil war as the newly immortal made bids for power. I'm not sure how that could be satisfactorily simulated in MA without turning it into LA Ulm with a weaker start.
As for Ermor, would be interesting if there was a spell that summoned some nice undead, places Twiceborn on the caster, causes a small amount of Insanity per cast, and ages them 5-10 years.
That could be fun for R'lyeh, too. Static summons for batches of Void creatures, but the spells cause Insanity.
