[P3D]

I'd prefer Minister of Magic for non-capital research. With M1, that's 6RP for 70g (4.67g/turn, 0.81g/RP/turn) vs 5RP for 100g (3.33g/turn, .67g/RP/turn). The difference is minimal.
And you can build MoM without temple or lab in your second fort, starting 7-9th turn.
Don't forget Fire Fetish. You can even heal back diseased commanders if you want.
If you choose Misfortune you 'd buy geomancers instead of them anyways.