[Grandpa Kim]

Fyron is right. Here are some more ideas:

The basics:
Ship and fleet training-- you gotta be able to hit him.
Fastest possible ships-- you gotta get to him before you are destroyed
Point Blank-- he may hit 10/10, but if you can hit 9/10....
These are absolutely necessary!

Other ideas
Ripper Beams-- big bang for the kt.
Strip out all armor and shields and go guns, guns, guns!-- untried by me, but sounds promising
Attack his planets-- but don't sit around, keep moving
Null Space as a secondary weapon-- maybe you hit the talisman first shot
Organic race and use that armor!-- so he hits, you just regenerate

Just my ideas, I'll bet there are hundreds more out there.

Kim