In addition to the TDM, also try set Computer player and computer AI bonuses to high. That should give you a run for your money.
There are also a few more mods out that make playing the game more challenging. Check them out as well.
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Creator of the Star Trek Mod - AST Mod - 78 Ship Sets - Conquest Mod - Atrocities Star Wars Mod - Galaxy Reborn Mod - and Subterfuge Mod.
And for the record, Space Empires IV was not developed by a huge conglomerate game development company, it was developed by only one man. Compare SEIV to MOO3 and see which is the better game.
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Creator of the Star Trek Mod - AST Mod - 78 Ship Sets - Conquest Mod - Atrocities Star Wars Mod - Galaxy Reborn Mod - and Subterfuge Mod.