I haven't played Dom2 much but there is a 1 handed sword in Dom3 (hellfire sword?) that requires earth and death to create. I think it requires construction 6. That thing rocks! Has a great AE.
I also like the boots that stop aging. I had a hero show up at my door and he started with the aging trait. Luckily he had the skills to make the aging boots so he made himself the boots.
Unluckily, he became diseased the same turn he created the boots!