Chalice and Amon Hotep

[Taqwus]

If you want truly obscene prot, go for an undead commander (Wraith Lords and Vampire Lords are the obvious picks, both being immortal, if you're not going to do this to a Prince of Death) since they basically ignore encumberance.

Then give 'em the flaming helmet (prot 7, and undead ignore the fatigue it gives, or at least did in Dom I), a good shield like the Aegis (hard to go wrong with "save or die" damage shields), and a heavy armor like Asfetik or Monolith. For even more prot consider the stoneskin boots instead of, say, quickness. At least in Dom I, you could get to 40.

Then your opponent hits you with armor negating effects.