Hell sword vs Wraith sword vs Blood thorn

[Chazar]

(This is interesting stuff, especially since I seem to experience cases where lifestealing is not so easy to come by (as oppossed to quantum_mechani). So let me assume again a scarce availability of adept forgers (i.e. not all paths available) and a scarce supply of gems (including blood slaves):

One of the things I fear most are battle afflictions. These can be prevented by:
a) Regeneration
b) High defensiveness: defense, protection, luck,..

So what are the experience-based advices in order to make the appearance of battle afflictions an unlikely event? Is high regeneration a must have? Is a PendantOfLuck better than a RingOfRegeneration in this respect? At which base protection is a high-protection armour better than a HydraSkin armor in order to prevent afflictions?

What about being cursed? Does a LuckyCoin cancel out a curse evenly? Is it generally stupid to send out a cursed pretender alone against masses of weaklings instead of still-useful-but-no-risk office duty?

(Actually for an example, I am sending a cursed[i] Titan pretender out against masses of human weaklings controlled by Marignon AI (J�rnsaxa in a Shepherd Game). She is currently equipped with
SnakeBladderStick
CharcoalShield
HyrdaSkinArmor
BootsOfQuickness
PendantOfLuck
BurningPearl
100% fire resistance seems useful vs. AI Marignon nevertheless it would really hurt to get e.g. the mindless affliction, so I wonder how to improve the mass killing capabilities while not getting hurt. I thought to add either a ring of Resilience or Regeneration (plus FireHelmet instead of BurningPearl). The script is SummonEarthpower, Personal Regeneration, Mistfrom and IronSkin in order provide some Reinvigoration and to decrease the affliction risk.)