Space Above & Beyond On DVD

[Suicide Junkie]

If you're only going to have 200 crew or so, the ship will be very very empty.

You could probably fill the empty space with lots of reactors, weapon ports, shield generation and armor. With a gaggle of technicians to keep things running.
Maybe an industrial-sized replicator so you can snatch a passing asteroid for mass and make big replacement parts like fighters/shuttles, torpedoes or even big reactors in one piece.