I use gimp to make sprites but actually I haven't really made much sprites.. I usually search the net (or basegame) for a sort of fitting image and the edit it.. I'm getting pretty good at the editting but I'm not an artist myself. We'll you have seen dominions 3000 so you know what I've done

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Want a blend of
fantasy and
sci-fi? Try the total conversion
Dominions 3000 mod with a new and fully modded solar system map.
Dragons wanted? Try the
Dragons, Magic Incarnate nation.
New and different undead nation? Try
Souls of Shiar. Including new powerfull holy magic.
In for a whole new sort of game? Then try my scenario map
Gang Wars.